Orlistat 120mg Capsules

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Orlistat is the only weight loss medication currently authorized in the EU. Orlistat prevents the absorption of fat from the food you consume. Orlistat is clinically proven to help you lose up to 50 percent more weight than dieting alone by decreasing the amount of fat absorbed.

Available in 2, 4, and 8 weeks packs.


What Exactly Is Orlistat?
Orlistat 120 mg is prescribed to treat obesity. Orlistat prevents the absorption of fat from the food you consume. By decreasing the amount of fat that is absorbed, Orlistat can facilitate weight loss.

What exactly is Xenical?
Xenical is the brand name for the generic medication Orlistat 120mg. Roche manufactures Xenical, which contains 120 mg of the active ingredient Orlistat. There is no difference between generic Orlistat and Xenical from a medical standpoint, but Orlistat is typically less expensive.

What is the nature of Alli?
Alli is the brand name for Orlistat 60mg and is available without a prescription. Alli is half as potent as Orlistat 120mg and Xenical, which are available only with a doctor’s prescription.

When should Orlistat be used?
If you have previously attempted to lose weight through diet and exercise without success, you may want to consider trying Orlistat. Orlistat is clinically proven to assist in 50% greater weight loss than dieting alone.

Orlistat is only appropriate for those with a BMI greater than 30 or for those with a BMI greater than 28 who have weight-related conditions such as diabetes or hypertension.

Utilize our BMI calculator online to determine your BMI.

How Does Orlistat Function?
Orlistat operates in a novel manner. Orlistat, the active ingredient, binds to some of the body’s natural enzymes that break down fat, preventing its absorption. This prevents the absorption of some of the fat you consume.

If you consume an excessive amount of fat or calories, your body stores the excess as fat, leading to weight gain. When you consume fat, your body breaks it down into its simplest components for digestion.

Orlistat works in your digestive system to prevent the digestion of approximately one-third of the fat in the food you eat.

Lipases are digestive enzymes that aid in fat digestion (or breakdown). When taken with meals, Orlistat binds to lipases and prevents them from breaking down a portion of the fat consumed.

Fat that has not been digested cannot be absorbed and is eliminated via bowel movements. In this manner, Orlistat prevents the absorption of approximately one-third of the fat in the foods you consume.

Orlistat is neither an appetite suppressant nor a stimulant. It is designed to only affect your digestive system and should not affect your heart rate, brain, or cause insomnia. The safety and efficacy of Orlistat have been established in over 100 clinical studies involving over 30,000 individuals.

When you begin taking Orlistat, you will be given a three-month weight loss goal. This objective is 5% of your weight. If you successfully lose 5 percent of your body weight, you can continue taking Orlistat. Orlistat can be supplied by pharmacists for up to two years.

Each time Orlistat is prescribed, you must provide your current weight to your pharmacist. If your weight increases within three months, Orlistat must be discontinued. If you lose enough weight for your BMI to drop below 28, Orlistat will no longer be available to you.

Some individuals fail to lose weight with Orlistat. These individuals should not lose hope. They can take a six-month break and try again later, or they can visit a doctor or a weight loss clinic. Weight loss, like many difficult goals, requires perseverance and determination, so do not give up.
How To Take

The recommended dose of Orlistat is one 120mg capsule taken orally with liquid at each main fat-containing meal. Orlistat should be taken up to three times per day in conjunction with a low-calorie diet. Each time you take Orlistat, your nutritionally-balanced meal should contain no more than 30 percent of its calories from fat.

You should divide your daily fat, carbohydrate, and protein intake evenly among your three main meals. Orlistat should be taken during or up to one hour after meals. If you occasionally skip meals or consume meals without fat, you can skip your Orlistat dose. Doses greater than 120 mg three times per day have not been shown to result in additional weight loss benefits. You should strive to adhere to a healthy diet, such as one that contains no more than 30 percent of calories from fat. Following this diet will help you lose weight and reduce some of the possible gastrointestinal side effects associated with Orlistat use.


Because Orlistat inhibits the absorption of certain fat-soluble vitamins, you should take a multivitamin supplement containing vitamins A, D, E, and K and beta carotene once a day, preferably at bedtime, at least two hours before or after taking Orlistat.

How Successful is Orlistat?

Orlistat has been studied extensively. In clinical trials, nearly twice as many patients who received Orlistat lost 10 percent or more of their body weight on average in one year compared to those who only followed a diet.


People treated with Orlistat and a low-calorie diet containing no more than 30 percent calories from fat lost significantly more weight than those treated with diet alone. All participants consumed a reduced-calorie diet for four weeks, followed by either the diet plus Orlistat or the diet alone for fifty-two weeks. After 52 weeks, those who took Orlistat plus diet lost twice as much weight on average as those who used diet alone (approximately 13.4 lbs versus 5.8 lbs). There is compelling scientific evidence that if you are obese, losing as little as 5 to 10 percent of your body weight can improve your health. In two-year studies of Orlistat, nearly 40 percent of individuals treated with Orlistat plus diet lost at least 5 percent of their body weight. In comparison, only 24% of those treated with diet alone were able to lose 5% of their body weight. Weight loss with Orlistat and a healthy diet reduces a number of health risks associated with obesity. Weight loss with Orlistat and a healthy diet reduces a number of health risks associated with obesity.


According to studies, weight loss with Orlistat can:

Reduce overall and LDL cholesterol (level of low-density lipoprotein-also known as bad cholesterol) total: -2.0 percent Orlistat vs. +5.0 percent placebo, LDL: -4.0 percent vs. +5.0 percent

Improve ratio of bad to good cholesterol (LDL/HDL cholesterol): -0.37 with Orlistat versus -0.22 with placebo.

Reduce blood pressure by -1.01 versus +0.58 mmHg systolic and -1.19 versus +0.46 mmHg diastolic.

High levels of the hormone insulin (which allows glucose or sugar to enter the body’s cells) are associated with coronary heart disease. -6.7 vs +5.2 pmol/L

Adverse Effects

Orlistat, like all medications, can cause side effects, although not everyone experiences them. The most frequent side effects of Orlistat are flatulence with or without oily spotting, sudden or increased bowel movements, and soft stools. These are caused by the way the capsules function and are the result of fat leaving the body. Typically, these effects occur within the first few weeks of taking the capsules, before you may have learned to limit the fat in your diet. These diet-related treatment effects may indicate that you have consumed an excessive amount of fat.


These diet-related treatment effects are largely attributable to what you eat, so consuming meals with less fat will help you manage them. The following advice will be useful:

Determine the typical fat content of your favorite foods and the size of your portions (check the labels). By becoming accustomed to the recommended portion sizes, you will be less likely to exceed your daily fat limit by accident.

Be patient. It may take some time to become familiar with your fat and calorie goals. The majority of patients who initially experience diet-related treatment side effects learn how to manage them.

A food diary is an invaluable tool for identifying which foods can cause diet-related treatment side effects. This booklet includes an example of how to keep a food diary as well as some blank diary pages so you can jot down helpful notes and favorite recipes – you’ll quickly get into the swing of things.

Information leaflet here.

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