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Perindopril is a medication that is a member of the ACE inhibitors (Angiotensin Converting Enzyme Inhibitors) class and is used to treat heart failure and high blood pressure.


Describe Perindopril.

Perindopril is a medication that is used to treat high blood pressure and heart failure. It is a member of the class of medications known as ACE inhibitors (Angiotensin Converting Enzyme Inhibitors).

Perindopril’s mechanism of action

In order to facilitate easier blood flow, Perindopril relaxes the blood arteries. Additionally, it makes it simpler for your heart to circulate blood throughout your entire body.

What advantages come with taking Perindopril?

Heart issues or high blood pressure (also known as hypertension) can be caused by a variety of things, including a family history, a salt-rich diet, being overweight, or not exercising enough.

It is frequently advised to take medicine, such as Perindopril, to treat the disorders in order to prevent more serious illnesses such as stroke, heart attack, or blood clots. These lifestyle modifications include quitting smoking, drinking less alcohol, and exercising more.

How should Perindopril be used?

Only people who have a prescription may take Perindopril. Always read the patient information sheet included in the drug packaging and abide by your doctor’s recommendations.

Preferably before a meal, swallow the tablets whole with a glass of water. To make sure you remember, take it at the same time every day.

Dosage of Perindopril

The active component of Perindopril, Perindopril arginine, is present at dosages of 2.5 mg, 5 mg, and 10 mg per tablet.

If your doctor determines you need it, the dosage for high blood pressure is typically increased to 10mg once daily from the standard starting dose of 5mg. This dose will be different if you are taking Perindopril for heart failure or other heart issues. You should always take the medication exactly as directed and consult your doctor if you have any questions.

You should skip the missed dose of Perindopril and immediately start taking the following one if you forget to take it. Do not increase your dose to make up for a missing one, but also do not be alarmed.

Visit your nearest emergency room or doctor right away if you take more Perindopril than is recommended. Low blood pressure, which can result from an overdose, can cause symptoms like lightheadedness or fainting.

Side effects and safety measures

You should always speak with your doctor before taking Perindopril. If you fit any of the following descriptions, you shouldn’t use Perindopril:

  • if any of the other components of this medication, including Perindopril, cause you to become allergic,
  • if you have previously used an ACE inhibitor and suffered symptoms like wheezing, swelling of the face, tongue, or throat, strong itching, or severe skin rashes
  • if you are expecting after three months
  • if you use a blood pressure-lowering medication containing aliskiren and you have diabetes or poor renal function,
  • if you undergo blood filtration procedures like dialysis,
  • if you have renal issues and your kidneys’ blood supply is compromised
  • if you are receiving heart failure treatment

You should let your doctor know if any of the following apply so they can consider how they might influence your prescription for Perindopril:

  • having a narrowed artery delivering blood to the kidneys or a narrowed major blood stream leaving the heart,
  • have any further heart issues,
  • a liver condition,
  • if you are on dialysis or have renal issues,
  • have unnaturally high quantities of the hormone aldosterone in your body
  • suffer from vascular collagen disease,
  • possess diabetes,
  • are on a salt-restricted diet or use potassium-containing salt substitutes,
  • are going to have significant surgery or anesthesia,
  • are scheduled for LDL apheresis
  • are undergoing desensitization therapy to lessen the consequences of a bee or wasp sting allergy,
  • have lately experienced vomiting or diarrhea, or are dehydrated,
  • your doctor has informed you that you are intolerant to some sweets,
  • are of African descent since you could be more susceptible to angioedema

Perindopril, like many drugs having active components, can have an impact on or interact with other drugs. You might encounter this with certain drugs, such as the following:

  • other high blood pressure medications
  • potassium-containing salt replacements, potassium supplements, or potassium-sparing medications
  • either mania or depression, lithium
  • medications that are non-steroidal anti-inflammatory
  • medications for diabetes
  • baclofen (used to treat muscle stiffness in diseases such as multiple sclerosis),
  • medications for the treatment of mental illnesses such schizophrenia, anxiety, and depression
  • immunosuppressants
  • trimethoprim (for the treatment of infections)
  • estramustine (used in cancer therapy),
  • sacubitril/valsartan (used to treat long-term heart failure)
  • allopurinol (for the treatment of gout),
  • procainamide (for the treatment of an irregular heart beat),
  • the vasodilators nitrates,
  • medications used to treat asthma, shock, and low blood pressure
  • salted gold (used to treat symptoms of rheumatoid arthritis)

You should let your doctor know if you take any of the aforementioned drugs so that they can recommend whether or not Perindopril is the best line of action for you.

You should combine your medication with some lifestyle modifications, such eating properly, exercising frequently, and abstaining from excessive smoking or drinking, just like everyone else who has high blood pressure or heart failure.

While you are taking this medicine, your doctor may also order routine blood pressure, renal function, and blood testing.

Perindopril’s most frequent negative effects include:

  • headache,
  • dizziness,
  • vertigo,
  • needles and threads
  • disruptions in eyesight,
  • tinnitus (sensation of noises in the ears),
  • cough,
  • breathing difficulty (dyspnoea),
  • stomach issues such as nausea, vomiting, and discomfort in the abdomen
  • allergy symptoms (such as skin rashes, itching),
  • muscular spasms
  • a sense of weakness

Inform your doctor straight away if you do encounter one or more of these side effects and they continue or get worse. If any severe side effects occur, you should also call your doctor.


Where can I purchase Perindopril online?

At My London Pharmacy, you can purchase Perindopril online without risk. Before your order is filled, you must first have an online consultation with a clinician. Perindopril will be the best treatment for your problem, according to the online consultation.

Delivery options

  • Free on orders over £20
  • £2.49 for orders up to £20
  • Delivered in 3-5 working days

Express delivery

  • Free on orders over £60
  • £4.49 on orders up to £60
  • Delivered Next Day if ordered before 3 pm Monday to Friday / Delivered Tuesday if ordered after 3pm Friday to Sunday

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