PrEP (pre-exposure prophylaxis)

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PrEP is an HIV (human immunodeficiency virus) prevention tablet that you can take if you’re HIV-negative but believe you’ll be exposed to the virus. It reduces your chances of contracting HIV.

The active chemicals in the pill are tenofovir disoproxil and emtricitabine, which belong to a class of drugs used to treat HIV infections.

  • (1 Month) 30 tablets £39.00 | (2 Months) 60 tablets £77.00 | (3 Months) 90 tablets £115.00



Is PrEP (generic Truvada) available?

You must be 18 or older and at a higher risk of contracting HIV to order PrEP from My London Pharmacy.

You must also have tested negative for HIV and hepatitis B and C, as well as have normal renal function.

If you do not use condoms during sex, you are more likely to contract HIV:

  • a man who engages in sex with other men
  • a transgender individual who has had intercourse with men
  • a lady who has sexual relations with bisexuals
  • a sex worker having intercourse with someone from a high-infection-rate nation
  • having intercourse with an HIV-positive person who has a detectable viral load (they have a high amount of the virus in their blood)
  • having sexual relations with someone whose HIV status is unknown
  • using needles, syringes, and other equipment to inject drugs and sharing them with others

Do I need to take a test before getting PrEP?

Before you may start taking PrEP, you must be HIV-negative, have normal kidney function, and be free of hepatitis B and C. PrEP tests can be ordered online from My London Pharmacy, and a sample can be taken at home and sent to our partner laboratory for analysis.

We have two types of PrEP tests: an introduction and yearly PrEP test, which you’ll need to do if you’ve never taken PrEP before or haven’t taken PrEP for a year, and a continuation PrEP test,

which you can take if you’ve already started taking PrEP:

Annual PrEP test and introduction This is a test for HIV, hepatitis B and C, and kidney function (creatinine and estimated Glomerular Filtration Rate; eGFR).
PrEP test continuation. This test looks for HIV as well as renal function (creatinine and estimated Glomerular Filtration Rate; eGFR). This is for those who know their hepatitis status or who have had hepatitis B vaccination and are at low risk of contracting hepatitis C.

If you haven’t already started taking PrEP, you’ll need to complete the introduction and yearly PrEP test. You’ll need to repeat the introduction and annual PrEP test once a year to ensure that PrEP is right for you.


Can I still get PrEP if I test negative for HIV but positive for hepatitis B or C or have impaired kidney function?


If you test positive for hepatitis, we’ll tell you to schedule an appointment with your primary care physician to be sent to a liver specialist.

If your kidney function is abnormal, you’ll be asked to repeat the test to see if it improves. We recommend that you see your doctor for this test since they will evaluate you and perform additional testing, but you can test with us again.

If your results require additional testing, you will not be able to take PrEP until you have received unequivocal evidence that it is safe for you.


Why is HIV-negative status crucial before and during PrEP therapy?


You must know your HIV status before using PrEP to ensure that the medicine is safe for you. This is due to the fact that PrEP comprises two types of antiviral drugs that are used in combination with other medications to treat HIV-positive people.

When you use the medications on their own while HIV positive, you risk becoming resistant to them, making future treatment of the illness more difficult.


What is the efficacy of PrEP?


PrEP is a powerful HIV prevention tool. When taken daily, PrEP reduces the chance of contracting HIV through sex by around 99 percent, according to studies.

When PrEP is not taken daily, it is substantially less effective unless it is part of a new, established regimen, such as the ‘on demand’ technique.


What is the procedure for taking PrEP?


There are several ways to take PrEP, depending on your present lifestyle and how often you are exposed to HIV-positive people. Although there are other options, we exclusively recommend daily PrEP dosing. This is because we can simply monitor how PrEP is affecting you and provide remote advise to ensure you’re getting the best possible medication.

PrEP every day

Daily PrEP should be taken at the same time each day and can be used for both anal and vaginal or frontal sex. After that, you’ll be safe:

  • Anal sex for 4 days
  • Vaginal sex for 7 days

PrEP should be taken with food at any time during the day, but at the same time each day.


Are there any negative consequences to taking PrEP?


When using PrEP, you may suffer certain negative effects, but these should subside after a few weeks. If the negative effects persist or become difficult to manage, you should consult your doctor before discontinuing PrEP.

The following are some common adverse effects:

  • nausea and vomiting
  • diarrhoea\sheadaches
  • weight loss dizziness feeling exhausted stomach pain feeling bloated
  • depression & back pain
  • skin irritation

Is PrEP affected by other medications or alcohol?


We’ll question you about any drugs you’re presently taking or have recently stopped taking before we may prescribe PrEP. This is because taking PrEP at the same time as some medications may impair PrEP’s HIV protection.

The following medications may impair PrEP protection:

  • treatment for fungal or viral infections
  • antibiotics
  • Hepatitis C cancer medicines and pain relievers

Although there are no known interactions between PrEP and alcohol, you should strive to consume the recommended units of alcohol each week to maintain your liver healthy.


Is PrEP available on the NHS?

PrEP is presently available for free through your local sexual health clinic on the NHS in England, Scotland, and Wales.

In Northern Ireland, PrEP is also available through GUM clinics, but only as part of a trial.


What is PrEP’s mechanism of action?

PrEP works by inhibiting an enzyme that prevents an HIV infection from multiplying in the body.


What does prophylaxis imply?


Prophylaxis is a form of drug that prevents you from contracting a disease, such as PrEP (pre-exposure prophylaxis).


Are there various kinds of PrEP?


In the UK, there are two types of PrEP:

Truvada is the branded type; generic PrEP is the more popular form.

Tenofovir disoproxil and emtricitabine are the two active components in both.


Is PrEP a cure for HIV?


PrEP is not an HIV cure, but it can help reduce your risk of contracting the virus if taken as directed by your doctor. We also recommend that you continue to use condoms because PrEP is only 95% effective.

Although there is no cure for HIV, it can be controlled with a combination of specialised antiviral medications that can help most HIV patients live a long and healthy life.


Can PrEP be used in place of PEP?


PrEP cannot be used as PEP. PEP (post-exposure prophylaxis) is not the same as PrEP (pre-exposure prophylaxis).

If you think you’ve been exposed to HIV, you should take PEP after having sex. It is normally recommended for a month and should be taken as soon as you suspect you have been exposed to the virus to protect you.

If you think you’ve been exposed, go to your local sexual health clinic, GP, or A&E department as away since you might be able to get PEP if you get treatment within 72 hours after infection.


Is PrEP effective in preventing other STIs?


PrEP will not protect you from other sexually transmitted diseases (STIs) such as chlamydia, gonorrhoea, syphilis, or herpes; instead, you should use condoms or other forms of protection.


When taking PrEP, how should I look after myself?


If you’re on PrEP, make sure you’re remaining healthy and that you’re still taking it. You’ll require:

a three-month check We’ll need to know that you’ve tested negative for HIV and have good kidney function every three months for an annual check. We’ll need to know every year that you’ve tested negative for HIV and hepatitis B and C, and that your kidney function is good.
Routine STI testing

Regular STI tests or screenings are recommended.

Obtaining assistance

Depending on your situation, you might find the following materials useful:

  • Mermaids can provide you with further information and support if you are transgender.
  • The National Health Service has information about psychological therapy.
  • The Gay Men’s Health Project provides information about HIV prevention and the stigma associated with the disease.
  • Your local sexual health clinic or Dean Street Clinic’s website can provide you with more information and help regarding drugs and chemsex.

What does it mean to be PrEP-negative?


You must maintain your ‘negative on PrEP’ status to continue taking PrEP safely. This implies you should get tested for HIV every three months to ensure you’re still HIV-free.

Delivery options

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  • £2.49 for orders up to £20
  • Delivered in 3-5 working days

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  • Free on orders over £60
  • £4.49 on orders up to £60
  • Delivered Next Day if ordered before 3 pm Monday to Friday / Delivered Tuesday if ordered after 3pm Friday to Sunday

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